Загрузка...

Expression and Regulation of Cyclic Nucleotide Phosphodiesterases in Human and Rat Pancreatic Islets

As shown by transgenic mouse models and by using phosphodiesterase 3 (PDE3) inhibitors, PDE3B has an important role in the regulation of insulin secretion in pancreatic β-cells. However, very little is known about the regulation of the enzyme. Here, we show that PDE3B is activated in response to hig...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Heimann, Emilia, Jones, Helena A., Resjö, Svante, Manganiello, Vincent C., Stenson, Lena, Degerman, Eva
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995729/
https://ncbi.nlm.nih.gov/pubmed/21152070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014191
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!