Advances in targeting cyclic nucleotide phosphodiesterases

Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolysis of cyclic AMP and cyclic GMP, thereby regulating the intracellular concentrations of these cyclic nucleotides, their signalling pathways and, consequently, myriad biological responses in health and disease. Currently, a small number...

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Hlavní autoři: Maurice, Donald H., Ke, Hengming, Ahmad, Faiyaz, Wang, Yousheng, Chung, Jay, Manganiello, Vincent C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155750/
https://ncbi.nlm.nih.gov/pubmed/24687066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4228
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