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Therapeutic targeting of 3’,5’-cyclic nucleotide phosphodiesterases: Inhibition and beyond
Phosphodiesterases (PDEs), enzymes that degrade 3’,5’-cyclic nucleotides, are being pursued as therapeutic targets for several diseases, including those affecting the nervous system, cardiovascular system, fertility, immunity, cancer, and metabolism. Clinical development programmes have focused excl...
Gardado en:
| Publicado en: | Nat Rev Drug Discov |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6773486/ https://ncbi.nlm.nih.gov/pubmed/31388135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-019-0033-4 |
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