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Activation of Group II Metabotropic Glutamate Receptors Inhibits Synaptic Excitation of the Substantia Nigra Pars Reticulata

Loss of nigrostriatal dopaminergic neurons in Parkinson's disease (PD) leads to increased activity of glutamatergic neurons in the subthalamic nucleus (STN). Recent studies reveal that the resultant increase in STN-induced excitation of basal ganglia output nuclei is responsible for the disabli...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Bradley, Stefania Risso, Marino, Michael J., Wittmann, Marion, Rouse, Susan T., Awad, Hazar, Levey, Allan I., Conn, P. Jeffrey
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773118/
https://ncbi.nlm.nih.gov/pubmed/10777772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-09-03085.2000
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