Activation of Group I Metabotropic Glutamate Receptors Produces a Direct Excitation and Disinhibition of GABAergic Projection Neurons in the Substantia Nigra Pars Reticulata

A pathological increase in excitatory glutamatergic input to substantia nigra pars reticulata (SNr) from the subthalamic nucleus (STN) is believed to play a key role in the pathophysiology of Parkinson's disease. We present an analysis of the physiological roles that group I metabotropic glutam...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Marino, Michael J., Wittmann, Marion, Bradley, Stefania Risso, Hubert, George W., Smith, Yoland, Conn, P. Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762993/
https://ncbi.nlm.nih.gov/pubmed/11549710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-18-07001.2001
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