Activation of Group II Metabotropic Glutamate Receptors Inhibits Synaptic Excitation of the Substantia Nigra Pars Reticulata

Loss of nigrostriatal dopaminergic neurons in Parkinson's disease (PD) leads to increased activity of glutamatergic neurons in the subthalamic nucleus (STN). Recent studies reveal that the resultant increase in STN-induced excitation of basal ganglia output nuclei is responsible for the disabli...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Bradley, Stefania Risso, Marino, Michael J., Wittmann, Marion, Rouse, Susan T., Awad, Hazar, Levey, Allan I., Conn, P. Jeffrey
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2000
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ARTICLE
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773118/
https://ncbi.nlm.nih.gov/pubmed/10777772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-09-03085.2000
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