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Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata

BACKGROUND AND PURPOSE: Increased firing of the glutamatergic pathway between the subthalamic nucleus and substantia nigra pars reticulata (SNpr) contributes to the abnormal firing of motor circuits and subsequent motor deficits seen in Parkinson's disease. Broad spectrum agonist-induced activa...

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Détails bibliographiques
Auteurs principaux: Broadstock, M, Austin, PJ, Betts, MJ, Duty, S
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346249/
https://ncbi.nlm.nih.gov/pubmed/21627638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01515.x
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