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A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission

One of the hallmarks of cancer is chromosome instability (CIN), which leads to aneuploidy, translocations, and other chromosome aberrations. However, in the vast majority of human tumors the molecular basis of CIN remains unknown, partly because not all genes controlling chromosome transmission have...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Liskovykh, Mikhail, Goncharov, Nikolay V., Petrov, Nikolai, Aksenova, Vasilisa, Pegoraro, Gianluca, Ozbun, Laurent L., Reinhold, William C., Varma, Sudhir, Dasso, Mary, Kumeiko, Vadim, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir, Kouprina, Natalay
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771407/
https://ncbi.nlm.nih.gov/pubmed/31515286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.254276.119
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