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Human artificial chromosome (HAC) for measuring chromosome instability (CIN) and identification of genes required for proper chromosome transmission

Chromosomal instability (CIN) is one of the characteristics of cancer inherent for tumor initiation and progression, which is defined as a persistent, high rate of gain/loss of whole chromosomes. In the vast majority of human tumors the molecular basis of CIN remains unknown. The development of a co...

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Bibliografski detalji
Izdano u:Exp Cell Res
Glavni autori: Kouprina, Natalay, Liskovykh, Mikhail, Petrov, Nikolai, Larionov, Vladimir
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029811/
https://ncbi.nlm.nih.gov/pubmed/31877307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2019.111805
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