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Human artificial chromosome (HAC) for measuring chromosome instability (CIN) and identification of genes required for proper chromosome transmission

Chromosomal instability (CIN) is one of the characteristics of cancer inherent for tumor initiation and progression, which is defined as a persistent, high rate of gain/loss of whole chromosomes. In the vast majority of human tumors the molecular basis of CIN remains unknown. The development of a co...

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Détails bibliographiques
Publié dans:Exp Cell Res
Auteurs principaux: Kouprina, Natalay, Liskovykh, Mikhail, Petrov, Nikolai, Larionov, Vladimir
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029811/
https://ncbi.nlm.nih.gov/pubmed/31877307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2019.111805
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