Development of a novel HAC-based “gain of signal” quantitative assay for measuring chromosome instability (CIN) in cancer cells

Accumulating data indicates that chromosome instability (CIN) common to cancer cells can be used as a target for cancer therapy. At present the rate of chromosome mis-segregation is quantified by laborious techniques such as coupling clonal cell analysis with karyotyping or fluorescence in situ hybr...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Kim, Jung-Hyun, Lee, Hee-Sheung, Lee, Nicholas C. O., Goncharov, Nikolay V., Kumeiko, Vadim, Masumoto, Hiroshi, Earnshaw, William C., Kouprina, Natalay, Larionov, Vladimir
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924756/
https://ncbi.nlm.nih.gov/pubmed/26943579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7854
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