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A new generation of human artificial chromosomes for functional genomics and gene therapy
Since their description in the late 1990s, human artificial chromosomes (HACs) carrying a functional kinetochore were considered as a promising system for gene delivery and expression with a potential to overcome many problems caused by the use of viral-based gene transfer systems. Indeed, HACs avoi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522797/ https://ncbi.nlm.nih.gov/pubmed/22907415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1113-3 |
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