Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System

[Image: see text] The production of cells capable of carrying multiple transgenes to Mb-size genomic loci has multiple applications in biomedicine and biotechnology. In order to achieve this goal, three key steps are required: (i) cloning of large genomic segments; (ii) insertion of multiple DNA blo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:ACS Synth Biol
Hlavní autoři: Lee, Nicholas C. O., Kim, Jung-Hyun, Petrov, Nikolai S., Lee, Hee-Sheung, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir, Kouprina, Natalay
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2017
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778389/
https://ncbi.nlm.nih.gov/pubmed/28799737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.7b00209
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky