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Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System
[Image: see text] The production of cells capable of carrying multiple transgenes to Mb-size genomic loci has multiple applications in biomedicine and biotechnology. In order to achieve this goal, three key steps are required: (i) cloning of large genomic segments; (ii) insertion of multiple DNA blo...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Synth Biol |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Chemical Society
2017
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| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5778389/ https://ncbi.nlm.nih.gov/pubmed/28799737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.7b00209 |
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