Organization of Synthetic Alphoid DNA Array in Human Artificial Chromosome (HAC) with a Conditional Centromere

Human artificial chromosomes (HACs) represent a novel promising episomal system for functional genomics, gene therapy and synthetic biology. HACs are engineered from natural and synthetic alphoid DNA arrays upon transfection into human cells. The use of HACs for gene expression studies requires the...

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Main Authors: Kouprina, Natalay, Samoshkin, Alexander, Erliandri, Indri, Nakano, Megumi, Lee, Hee-Sheung, Fu, Haiging, Iida, Yuichi, Aladjem, Mirit, Oshimura, Mitsuo, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568986/
https://ncbi.nlm.nih.gov/pubmed/23411994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb3000436
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