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Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells
Telomerase/telomere-targeting therapy is a potentially promising approach for cancer treatment because even transient telomere dysfunction can induce chromosomal instability (CIN) and may be a barrier to tumor growth. We recently developed a dual-HAC (Human Artificial Chromosome) assay that enables...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8310675/ https://ncbi.nlm.nih.gov/pubmed/34316326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.28020 |
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