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Novel screen for anti-cancer drugs that elevate chromosome instability (CIN) using human artificial chromosome (HAC)
Human artificial chromosomes (HACs) bearing functional kinetochores have been exploited as promising systems for gene delivery and expression and in studies of different epigenetic modifications on kinetochore structure and function. The HAC-based technology has been also used to develop drug screen...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6305142/ https://ncbi.nlm.nih.gov/pubmed/30627324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26406 |
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