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Novel screen for anti-cancer drugs that elevate chromosome instability (CIN) using human artificial chromosome (HAC)

Human artificial chromosomes (HACs) bearing functional kinetochores have been exploited as promising systems for gene delivery and expression and in studies of different epigenetic modifications on kinetochore structure and function. The HAC-based technology has been also used to develop drug screen...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Kouprina, Natalay, Pommier, Yves, Larionov, Vladimir
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305142/
https://ncbi.nlm.nih.gov/pubmed/30627324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26406
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