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Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies
[Image: see text] It is generally accepted that chromatin containing the histone H3 variant CENP-A is an epigenetic mark maintaining centromere identity. However, the pathways leading to the formation and maintenance of centromere chromatin remain poorly characterized due to difficulties of analysis...
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| Veröffentlicht in: | ACS Synth Biol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2018
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5951608/ https://ncbi.nlm.nih.gov/pubmed/29565577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.8b00018 |
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