Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies

[Image: see text] It is generally accepted that chromatin containing the histone H3 variant CENP-A is an epigenetic mark maintaining centromere identity. However, the pathways leading to the formation and maintenance of centromere chromatin remain poorly characterized due to difficulties of analysis...

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Bibliografiske detaljer
Udgivet i:ACS Synth Biol
Main Authors: Pesenti, Elisa, Kouprina, Natalay, Liskovykh, Mikhail, Aurich-Costa, Joan, Larionov, Vladimir, Masumoto, Hiroshi, Earnshaw, William C., Molina, Oscar
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2018
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951608/
https://ncbi.nlm.nih.gov/pubmed/29565577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.8b00018
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