Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTA(VP64) expression cassette

Human artificial chromosome (HAC)-based vectors represent an alternative technology for gene delivery and expression with a potential to overcome the problems caused by virus-based vectors. The recently developed alphoid(tetO)-HAC has an advantage over other HAC vectors because it can be easily elim...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Kononenko, Artem V., Lee, Nicholas C.O., Liskovykh, Mikhail, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir, Kouprina, Natalay
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482055/
https://ncbi.nlm.nih.gov/pubmed/25712097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv124
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