A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission

One of the hallmarks of cancer is chromosome instability (CIN), which leads to aneuploidy, translocations, and other chromosome aberrations. However, in the vast majority of human tumors the molecular basis of CIN remains unknown, partly because not all genes controlling chromosome transmission have...

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Detalles Bibliográficos
Publicado en:Genome Res
Autores principales: Liskovykh, Mikhail, Goncharov, Nikolay V., Petrov, Nikolai, Aksenova, Vasilisa, Pegoraro, Gianluca, Ozbun, Laurent L., Reinhold, William C., Varma, Sudhir, Dasso, Mary, Kumeiko, Vadim, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir, Kouprina, Natalay
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Method
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771407/
https://ncbi.nlm.nih.gov/pubmed/31515286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.254276.119
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