A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission

One of the hallmarks of cancer is chromosome instability (CIN), which leads to aneuploidy, translocations, and other chromosome aberrations. However, in the vast majority of human tumors the molecular basis of CIN remains unknown, partly because not all genes controlling chromosome transmission have...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Liskovykh, Mikhail, Goncharov, Nikolay V., Petrov, Nikolai, Aksenova, Vasilisa, Pegoraro, Gianluca, Ozbun, Laurent L., Reinhold, William C., Varma, Sudhir, Dasso, Mary, Kumeiko, Vadim, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir, Kouprina, Natalay
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771407/
https://ncbi.nlm.nih.gov/pubmed/31515286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.254276.119
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