A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission

One of the hallmarks of cancer is chromosome instability (CIN), which leads to aneuploidy, translocations, and other chromosome aberrations. However, in the vast majority of human tumors the molecular basis of CIN remains unknown, partly because not all genes controlling chromosome transmission have...

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Gepubliceerd in:Genome Res
Hoofdauteurs: Liskovykh, Mikhail, Goncharov, Nikolay V., Petrov, Nikolai, Aksenova, Vasilisa, Pegoraro, Gianluca, Ozbun, Laurent L., Reinhold, William C., Varma, Sudhir, Dasso, Mary, Kumeiko, Vadim, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir, Kouprina, Natalay
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771407/
https://ncbi.nlm.nih.gov/pubmed/31515286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.254276.119
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