NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress

Base excision repair (BER) functions not only in the maintenance of genomic integrity but also in active DNA demethylation and epigenetic gene regulation. This dual role raises the question if phenotypic abnormalities resulting from deficiency of BER factors are due to DNA damage or impaired DNA dem...

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Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Han, Dandan, Schomacher, Lars, Schüle, Katrin M, Mallick, Medhavi, Musheev, Michael U, Karaulanov, Emil, Krebs, Laura, von Seggern, Annika, Niehrs, Christof
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
Soggetti:
Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768664/
https://ncbi.nlm.nih.gov/pubmed/31566562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49044
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