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NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress
Base excision repair (BER) functions not only in the maintenance of genomic integrity but also in active DNA demethylation and epigenetic gene regulation. This dual role raises the question if phenotypic abnormalities resulting from deficiency of BER factors are due to DNA damage or impaired DNA dem...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6768664/ https://ncbi.nlm.nih.gov/pubmed/31566562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49044 |
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