NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress

Base excision repair (BER) functions not only in the maintenance of genomic integrity but also in active DNA demethylation and epigenetic gene regulation. This dual role raises the question if phenotypic abnormalities resulting from deficiency of BER factors are due to DNA damage or impaired DNA dem...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Han, Dandan, Schomacher, Lars, Schüle, Katrin M, Mallick, Medhavi, Musheev, Michael U, Karaulanov, Emil, Krebs, Laura, von Seggern, Annika, Niehrs, Christof
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2019
Onderwerpen:
Developmental Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768664/
https://ncbi.nlm.nih.gov/pubmed/31566562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49044
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