NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress

Base excision repair (BER) functions not only in the maintenance of genomic integrity but also in active DNA demethylation and epigenetic gene regulation. This dual role raises the question if phenotypic abnormalities resulting from deficiency of BER factors are due to DNA damage or impaired DNA dem...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Han, Dandan, Schomacher, Lars, Schüle, Katrin M, Mallick, Medhavi, Musheev, Michael U, Karaulanov, Emil, Krebs, Laura, von Seggern, Annika, Niehrs, Christof
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2019
Pynciau:
Developmental Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768664/
https://ncbi.nlm.nih.gov/pubmed/31566562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49044
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