NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress

Base excision repair (BER) functions not only in the maintenance of genomic integrity but also in active DNA demethylation and epigenetic gene regulation. This dual role raises the question if phenotypic abnormalities resulting from deficiency of BER factors are due to DNA damage or impaired DNA dem...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Han, Dandan, Schomacher, Lars, Schüle, Katrin M, Mallick, Medhavi, Musheev, Michael U, Karaulanov, Emil, Krebs, Laura, von Seggern, Annika, Niehrs, Christof
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Assuntos:
Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768664/
https://ncbi.nlm.nih.gov/pubmed/31566562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49044
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