The ghrelin O-acyltransferase structure reveals a catalytic channel for transmembrane hormone acylation

Integral membrane proteins represent a large and diverse portion of the proteome and are often recalcitrant to purification, impeding studies essential for understanding protein structure and function. By combining co-evolutionary constraints and computational modeling with biochemical validation th...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Campaña, Maria B., Irudayanathan, Flaviyan Jerome, Davis, Tasha R., McGovern-Gooch, Kayleigh R., Loftus, Rosemary, Ashkar, Mohammad, Escoffery, Najae, Navarro, Melissa, Sieburg, Michelle A., Nangia, Shikha, Hougland, James L.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Accelerated Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768652/
https://ncbi.nlm.nih.gov/pubmed/31413115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC119.009749
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items