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Computational Nanoscopy of Tight Junctions at the Blood–Brain Barrier Interface

The selectivity of the blood–brain barrier (BBB) is primarily maintained by tight junctions (TJs), which act as gatekeepers of the paracellular space by blocking blood-borne toxins, drugs, and pathogens from entering the brain. The BBB presents a significant challenge in designing neurotherapeutics,...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Rajagopal, Nandhini, Irudayanathan, Flaviyan Jerome, Nangia, Shikha
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888702/
https://ncbi.nlm.nih.gov/pubmed/31717316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20225583
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