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Computational Nanoscopy of Tight Junctions at the Blood–Brain Barrier Interface

The selectivity of the blood–brain barrier (BBB) is primarily maintained by tight junctions (TJs), which act as gatekeepers of the paracellular space by blocking blood-borne toxins, drugs, and pathogens from entering the brain. The BBB presents a significant challenge in designing neurotherapeutics,...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Rajagopal, Nandhini, Irudayanathan, Flaviyan Jerome, Nangia, Shikha
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888702/
https://ncbi.nlm.nih.gov/pubmed/31717316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20225583
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