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Claudin-12 is not required for blood–brain barrier tight junction function

BACKGROUND: The blood–brain barrier (BBB) ensures central nervous system (CNS) homeostasis by strictly controlling the passage of molecules and solutes from the bloodstream into the CNS. Complex and continuous tight junctions (TJs) between brain endothelial cells block uncontrolled paracellular diff...

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Bibliographic Details
Published in:Fluids Barriers CNS
Main Authors: Castro Dias, Mariana, Coisne, Caroline, Baden, Pascale, Enzmann, Gaby, Garrett, Lillian, Becker, Lore, Hölter, Sabine M., Hrabě de Angelis, Martin, Deutsch, Urban, Engelhardt, Britta
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739961/
https://ncbi.nlm.nih.gov/pubmed/31511021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0150-9
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