A molecular switch in mouse CD1d modulates natural killer T cell activation by α-galactosylsphingamides

Type I natural killer T (NKT) cells are a population of innate like T lymphocytes that rapidly respond to α-GalCer presented by CD1d via the production of both pro- and anti-inflammatory cytokines. While developing novel α-GalCer analogs that were meant to be utilized as potential adjuvants because...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Wang, Jing, Guillaume, Joren, Janssens, Jonas, Remesh, Soumya G., Ying, Ge, Bitra, Aruna, Van Calenbergh, Serge, Zajonc, Dirk M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768634/
https://ncbi.nlm.nih.gov/pubmed/31391251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009963
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