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A molecular switch in mouse CD1d modulates natural killer T cell activation by α-galactosylsphingamides
Type I natural killer T (NKT) cells are a population of innate like T lymphocytes that rapidly respond to α-GalCer presented by CD1d via the production of both pro- and anti-inflammatory cytokines. While developing novel α-GalCer analogs that were meant to be utilized as potential adjuvants because...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6768634/ https://ncbi.nlm.nih.gov/pubmed/31391251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009963 |
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