SCF(FBXW7)-mediated degradation of p53 promotes cell recovery after UV-induced DNA damage

Eukaryotic cells have developed sophisticated mechanisms to ensure the integrity of the genome and prevent the transmission of altered genetic information to daughter cells. If this control system fails, accumulation of mutations would increase risk of diseases such as cancer. Ubiquitylation, an ess...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FASEB J
Egile Nagusiak: Galindo-Moreno, María, Giráldez, Servando, Limón-Mortés, M. Cristina, Belmonte-Fernández, Alejandro, Reed, Steven I., Sáez, Carmen, Japón, Miguel Á., Tortolero, Maria, Romero, Francisco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Federation of American Societies for Experimental Biology 2019
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766643/
https://ncbi.nlm.nih.gov/pubmed/31337255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900885R
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