SCF(FBXW7)-mediated degradation of p53 promotes cell recovery after UV-induced DNA damage

Eukaryotic cells have developed sophisticated mechanisms to ensure the integrity of the genome and prevent the transmission of altered genetic information to daughter cells. If this control system fails, accumulation of mutations would increase risk of diseases such as cancer. Ubiquitylation, an ess...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Galindo-Moreno, María, Giráldez, Servando, Limón-Mortés, M. Cristina, Belmonte-Fernández, Alejandro, Reed, Steven I., Sáez, Carmen, Japón, Miguel Á., Tortolero, Maria, Romero, Francisco
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766643/
https://ncbi.nlm.nih.gov/pubmed/31337255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900885R
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