The Trials and Tribulations of Structure Assisted Design of K(Ca) Channel Activators

Calcium-activated K(+) channels constitute attractive targets for the treatment of neurological and cardiovascular diseases. To explain why certain 2-aminobenzothiazole/oxazole-type K(Ca) activators (SKAs) are K(Ca)3.1 selective we previously generated homology models of the C-terminal calmodulin-bi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Shim, Heesung, Brown, Brandon M., Singh, Latika, Singh, Vikrant, Fettinger, James C., Yarov-Yarovoy, Vladimir, Wulff, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764326/
https://ncbi.nlm.nih.gov/pubmed/31616290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00972
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados