New Positive Ca(2+)-Activated K(+) Channel Gating Modulators with Selectivity for K(Ca)3.1

Small-conductance (K(Ca)2) and intermediate-conductance (K(Ca)3.1) calcium-activated K(+) channels are voltage-independent and share a common calcium/calmodulin-mediated gating mechanism. Existing positive gating modulators like EBIO, NS309, or SKA-31 activate both K(Ca)2 and K(Ca)3.1 channels with...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Coleman, Nichole, Brown, Brandon M., Oliván-Viguera, Aida, Singh, Vikrant, Olmstead, Marilyn M., Valero, Marta Sofia, Köhler, Ralf, Wulff, Heike
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2014
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152908/
https://ncbi.nlm.nih.gov/pubmed/24958817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.093286
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky