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Pharmacological gating modulation of small- and intermediate-conductance Ca(2+)-activated K(+) channels (K(Ca)2.x and K(Ca)3.1)

This short review discusses pharmacological modulation of the opening/closing properties (gating) of small- and intermediate-conductance Ca(2+)-activated K(+) channels (K(Ca)2 and K(Ca)3.1) with special focus on mechanisms-of-action, selectivity, binding sites, and therapeutic potentials. Despite K(...

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Publicat a:Channels (Austin)
Autors principals: Christophersen, Palle, Wulff, Heike
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group, LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850045/
https://ncbi.nlm.nih.gov/pubmed/26217968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2015.1071748
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