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Novel Phenolic Inhibitors of Small/Intermediate-Conductance Ca(2+)-Activated K(+) Channels, KCa3.1 and KCa2.3

BACKGROUND: KCa3.1 channels are calcium/calmodulin-regulated voltage-independent K(+) channels that produce membrane hyperpolarization and shape Ca(2+)-signaling and thereby physiological functions in epithelia, blood vessels, and white and red blood cells. Up-regulation of KCa3.1 is evident in fibr...

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Detalhes bibliográficos
Main Authors: Oliván-Viguera, Aida, Valero, Marta Sofía, Murillo, María Divina, Wulff, Heike, García-Otín, Ángel-Luis, Arbonés-Mainar, José-Miguel, Köhler, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597730/
https://ncbi.nlm.nih.gov/pubmed/23516517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058614
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