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Pharmacological characterization of small-conductance Ca(2+)-activated K(+) channels stably expressed in HEK 293 cells

1. Three genes encode the small-conductance Ca(2+)-activated K(+) channels (SK channels). We have stably expressed hSK1 and rSK2 in HEK 293 cells and addressed the pharmacology of these subtypes using whole-cell patch clamp recordings. 2. The bee venom peptide apamin blocked hSK1 as well as rSK2 wit...

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Hlavní autoři: Strøbæk, Dorte, Jørgensen, Tino D, Christophersen, Palle, Ahring, Philip K, Olesen, Søren-Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571906/
https://ncbi.nlm.nih.gov/pubmed/10696100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703120
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