Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions

DNA methylation regulates gene expression in a variety of processes, including mouse embryonic development. Four catalytically active enzymes function in mice as DNA methyltransferases (Dnmts) and as transcriptional regulators. Inactivation of Dnmt3b results in mouse embryonic lethality, but which a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Nowialis, Pawel, Lopusna, Katarina, Opavska, Jana, Haney, Staci L., Abraham, Ajay, Sheng, Peike, Riva, Alberto, Natarajan, Amarnath, Guryanova, Olga, Simpson, Melanie, Hlady, Ryan, Xie, Mingyi, Opavsky, Rene
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763448/
https://ncbi.nlm.nih.gov/pubmed/31558711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12355-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados