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Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling

BACKGROUND: DNA methylation regulates gene transcription in many physiological processes in mammals including development and haematopoiesis. It is catalysed by several DNA methyltransferases, including Dnmt3b that mediates both methylation-dependant and independent gene repression. Dnmt3b is critic...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Lopusna, Katarina, Nowialis, Pawel, Opavska, Jana, Abraham, Ajay, Riva, Alberto, Opavsky, Rene
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804970/
https://ncbi.nlm.nih.gov/pubmed/33418509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103191
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