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Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice

DNA methylation regulates gene transcription and is involved in various physiological processes in mammals, including development and hematopoiesis. It is catalyzed by DNA methyltransferases including Dnmt1, Dnmt3a, and Dnmt3b. For Dnmt3b, its effects on transcription can result from its own DNA met...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lopusna, Katarina, Nowialis, Pawel, Opavska, Jana, Abraham, Ajay, Riva, Alberto, Haney, Staci L., Opavsky, Rene
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949038/
https://ncbi.nlm.nih.gov/pubmed/33450231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100285
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