Loss of Dnmt3a induces CLL and PTCL with distinct methylomes and transcriptomes in mice

Cytosine methylation of DNA is an epigenetic modification involved in the repression of genes that affect biological processes including hematopoiesis. It is catalyzed by DNA methyltransferases, one of which -DNMT3A- is frequently mutated in human hematologic malignancies. We have previously reporte...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Haney, Staci L., Upchurch, Garland M., Opavska, Jana, Klinkebiel, David, Appiah, Adams Kusi, Smith, Lynette M., Heavican, Tayla B., Iqbal, Javeed, Joshi, Shantaram, Opavsky, Rene
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039761/
https://ncbi.nlm.nih.gov/pubmed/27677595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34222
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak