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Aberrant Promoter Hypomethylation in CLL: Does It Matter for Disease Development?

Over the last 30 years, studies of aberrant DNA methylation in hematologic malignancies have been dominated by the primary focus of understanding promoter hypermethylation. These efforts not only resulted in a better understanding of the basis of epigenetic silencing of tumor suppressor genes but al...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Upchurch, Garland Michael, Haney, Staci L., Opavsky, Rene
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980682/
https://ncbi.nlm.nih.gov/pubmed/27563627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00182
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