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Aberrant Promoter Hypomethylation in CLL: Does It Matter for Disease Development?

Over the last 30 years, studies of aberrant DNA methylation in hematologic malignancies have been dominated by the primary focus of understanding promoter hypermethylation. These efforts not only resulted in a better understanding of the basis of epigenetic silencing of tumor suppressor genes but al...

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Détails bibliographiques
Publié dans:Front Oncol
Auteurs principaux: Upchurch, Garland Michael, Haney, Staci L., Opavsky, Rene
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980682/
https://ncbi.nlm.nih.gov/pubmed/27563627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00182
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