Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

Dose is an important parameter in terms of both efficacy and adverse effects in pharmacological treatment of atrial fibrillation (AF). Both of the class III antiarrhythmics dofetilide and amiodarone have documented anti-AF effects. While dofetilide has dose-related ventricular side effects, amiodaro...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Pflugers Arch
Главные авторы: Kirchhoff, Jeppe Egedal, Diness, Jonas Goldin, Abildgaard, Lea, Sheykhzade, Majid, Grunnet, Morten, Jespersen, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2016
Предметы:
Ion Channels, Receptors and Transporters
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763419/
https://ncbi.nlm.nih.gov/pubmed/27722784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1883-9
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы