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Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses

BACKGROUND: Antiarrhythmic compounds against atrial fibrillation (AF) often have reduced efficacy and may display cardiac and/or noncardiac toxicity. Efficacy can be improved by combining 2 compounds with distinct mechanisms, and it may be possible to use lower doses of each compound, thereby reduci...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Carstensen, Helena, Kjær, Line, Haugaard, Maria Mathilde, Flethøj, Mette, Hesselkilde, Eva Zander, Kanters, Jørgen K., Pehrson, Steen, Buhl, Rikke, Jespersen, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Journal of Cardiovascular Pharmacology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768216/
https://ncbi.nlm.nih.gov/pubmed/29068807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000541
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