Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma

BACKGROUND: Adenoid cystic carcinoma (ACC) is a rare malignancy arising in salivary glands and other sites, characterized by high rates of relapse and distant spread. Recurrent/metastatic (R/M) ACCs are generally incurable, due to a lack of active systemic therapies. To improve outcomes, deeper unde...

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Publicat a:J Clin Invest
Autors principals: Ho, Allen S., Ochoa, Angelica, Jayakumaran, Gowtham, Zehir, Ahmet, Valero Mayor, Cristina, Tepe, Justin, Makarov, Vladimir, Dalin, Martin G., He, Jie, Bailey, Mark, Montesion, Meagan, Ross, Jeffrey S., Miller, Vincent A., Chan, Lindsay, Ganly, Ian, Dogan, Snjezana, Katabi, Nora, Tsipouras, Petros, Ha, Patrick, Agrawal, Nishant, Solit, David B., Futreal, P. Andrew, El Naggar, Adel K., Reis-Filho, Jorge S., Weigelt, Britta, Ho, Alan L., Schultz, Nikolaus, Chan, Timothy A., Morris, Luc G.T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Clinical Medicine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763222/
https://ncbi.nlm.nih.gov/pubmed/31483290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128227
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