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Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma

BACKGROUND: Adenoid cystic carcinoma (ACC) is a rare malignancy arising in salivary glands and other sites, characterized by high rates of relapse and distant spread. Recurrent/metastatic (R/M) ACCs are generally incurable, due to a lack of active systemic therapies. To improve outcomes, deeper unde...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Ho, Allen S., Ochoa, Angelica, Jayakumaran, Gowtham, Zehir, Ahmet, Valero Mayor, Cristina, Tepe, Justin, Makarov, Vladimir, Dalin, Martin G., He, Jie, Bailey, Mark, Montesion, Meagan, Ross, Jeffrey S., Miller, Vincent A., Chan, Lindsay, Ganly, Ian, Dogan, Snjezana, Katabi, Nora, Tsipouras, Petros, Ha, Patrick, Agrawal, Nishant, Solit, David B., Futreal, P. Andrew, El Naggar, Adel K., Reis-Filho, Jorge S., Weigelt, Britta, Ho, Alan L., Schultz, Nikolaus, Chan, Timothy A., Morris, Luc G.T.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2019
Subjects:
Clinical Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763222/
https://ncbi.nlm.nih.gov/pubmed/31483290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128227
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