Comprehensive molecular characterization of salivary duct carcinoma reveals actionable targets and similarity to apocrine breast cancer

PURPOSE: Salivary duct carcinoma (SDC) is an aggressive salivary malignancy which is resistant to chemotherapy and has high mortality rates. We investigated the molecular landscape of SDC, focusing on genetic alterations and gene expression profiles. EXPERIMENTAL DESIGN: We performed whole-exome seq...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Dalin, Martin G., Desrichard, Alexis, Katabi, Nora, Makarov, Vladimir, Walsh, Logan A., Lee, Ken-Wing, Wang, Qingguo, Armenia, Joshua, West, Lyndsay, Dogan, Snjezana, Wang, Lu, Ramaswami, Deepa, Ho, Alan L., Ganly, Ian, Solit, David B., Berger, Michael F., Schultz, Nikolaus D., Reis-Filho, Jorge S., Chan, Timothy A., Morris, Luc G.T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026550/
https://ncbi.nlm.nih.gov/pubmed/27103403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0637
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge