Comprehensive molecular characterization of salivary duct carcinoma reveals actionable targets and similarity to apocrine breast cancer

PURPOSE: Salivary duct carcinoma (SDC) is an aggressive salivary malignancy which is resistant to chemotherapy and has high mortality rates. We investigated the molecular landscape of SDC, focusing on genetic alterations and gene expression profiles. EXPERIMENTAL DESIGN: We performed whole-exome seq...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Dalin, Martin G., Desrichard, Alexis, Katabi, Nora, Makarov, Vladimir, Walsh, Logan A., Lee, Ken-Wing, Wang, Qingguo, Armenia, Joshua, West, Lyndsay, Dogan, Snjezana, Wang, Lu, Ramaswami, Deepa, Ho, Alan L., Ganly, Ian, Solit, David B., Berger, Michael F., Schultz, Nikolaus D., Reis-Filho, Jorge S., Chan, Timothy A., Morris, Luc G.T.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026550/
https://ncbi.nlm.nih.gov/pubmed/27103403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0637
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