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The Mutational Landscape of Adenoid Cystic Carcinoma

Adenoid cystic carcinomas (ACCs) are among the most enigmatic of human malignancies. These aggressive salivary cancers frequently recur and metastasize despite definitive treatment, with no known effective chemotherapy regimen. Here, we determined the ACC mutational landscape and report the exome or...

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Autores principales: Ho, Allen S., Kannan, Kasthuri, Roy, David M., Morris, Luc G.T., Ganly, Ian, Katabi, Nora, Ramaswami, Deepa, Walsh, Logan A., Eng, Stephanie, Huse, Jason T., Zhang, Jianan, Dolgalev, Igor, Huberman, Kety, Heguy, Adriana, Viale, Agnes, Drobnjak, Marija, Leversha, Margaret A., Rice, Christine E., Singh, Bhuvanesh, Iyer, N. Gopalakrishna, Leemans, C. Rene, Bloemena, Elisabeth, Ferris, Robert L., Seethala, Raja R., Gross, Benjamin E., Liang, Yupu, Sinha, Rileen, Peng, Luke, Raphael, Benjamin J., Turcan, Sevin, Gong, Yongxing, Schultz, Nikolaus, Kim, Seungwon, Chiosea, Simion, Shah, Jatin P., Sander, Chris, Lee, William, Chan, Timothy A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708595/
https://ncbi.nlm.nih.gov/pubmed/23685749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2643
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