Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma

BACKGROUND: Adenoid cystic carcinoma (ACC) is a rare malignancy arising in salivary glands and other sites, characterized by high rates of relapse and distant spread. Recurrent/metastatic (R/M) ACCs are generally incurable, due to a lack of active systemic therapies. To improve outcomes, deeper unde...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ho, Allen S., Ochoa, Angelica, Jayakumaran, Gowtham, Zehir, Ahmet, Valero Mayor, Cristina, Tepe, Justin, Makarov, Vladimir, Dalin, Martin G., He, Jie, Bailey, Mark, Montesion, Meagan, Ross, Jeffrey S., Miller, Vincent A., Chan, Lindsay, Ganly, Ian, Dogan, Snjezana, Katabi, Nora, Tsipouras, Petros, Ha, Patrick, Agrawal, Nishant, Solit, David B., Futreal, P. Andrew, El Naggar, Adel K., Reis-Filho, Jorge S., Weigelt, Britta, Ho, Alan L., Schultz, Nikolaus, Chan, Timothy A., Morris, Luc G.T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763222/
https://ncbi.nlm.nih.gov/pubmed/31483290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128227
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