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Non-Fc-Mediated Mechanisms Are Involved in Clearance of Amyloid-β In Vivo by Immunotherapy

Transgenic (Tg) mouse models overexpressing amyloid precursor protein (APP) develop senile plaques similar to those found in Alzheimer's disease in an age-dependent manner. Recent reports demonstrated that immunotherapy is effective at preventing or removing amyloid-β deposits in the mouse mode...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Bacskai, Brian J., Kajdasz, Stephen T., McLellan, Megan E., Games, Dora, Seubert, Peter, Schenk, Dale, Hyman, Bradley T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758112/
https://ncbi.nlm.nih.gov/pubmed/12223540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-18-07873.2002
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